Recent Publications
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Progeria-based vascular model identifies networks associated with cardiovascular aging and disease
Aging Cell. 2024;00:e14150.
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Tissue-Specific Tumour Suppressor and Oncogenic Activities of the Polycomb-like Protein MTF2
Genes 2023 Sep 27, 14(10), 1879;
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Tissue-Engineered Disease Modeling of Lymphangioleiomyomatosis Exposes a TherapeuticVulnerability to HDAC Inhibition
Adv Sci (Weinh). 2023 Jul 3;e2302611.
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Differentiation and single-cell RNA-seq analyses of human pluripotent-stem-cell-derived renal organoids
STAR Protoc. 2023 May 22;4(2):102314
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Tuberous sclerosis complex kidney lesion pathogenesis: a developmental perspective
J Am Soc Nephrol. 2023 Apr 15
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Erratum: Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum
Theranostics. 2023 Jan 9;13(2):867-869
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Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron
iScience. 2022 Oct 10;105316
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Renal organoid modeling of tuberous sclerosis complex reveals lesion features arise from diverse developmental processes
Cell Rep . 2022 Jul 5;40(1):111048
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Organelle Cooperation in Stem Cell Fate: Lysosomes as Emerging Regulators of Cell Identity
Front Cell Dev Biol. 2020 Jul 7;8:591
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Proteome-wide Prediction of Lysine Methylation Leads to Identification of H2BK43 Methylation and Outlines the Potential Methyllysine Proteome
Cell Rep. 2020 Jul 14;32(2):107896
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Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice
Nat Neurosci. 2020 Sep;23(9):1090-1101
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Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts
Sci Rep. 2020 Apr 22;10(1):6827
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Transcriptomically Guided Mesendoderm Induction of Human Pluripotent Stem Cells Using a Systematically Defined Culture Scheme
Stem Cell Reports. 2019 Dec 10;13(6):1111-1125
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Development of a novel screening platform for the identification of small molecule inhibitors of human adenovirus
Virology. 2019 Dec;538:24-34
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Gene expression profiling of skeletal myogenesis in human embryonic stem cells reveals a potential cascade of transcription factors regulating stages of myogenesis, including quiescent/activated satellite cell-like gene expression
PLoS One. 2019 Sep 27;14(9):e0222946
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Evaluating dose-limiting toxicities of MDM2 inhibitors in patients with solid organ and hematologic malignancies: A systematic review of the literature
Leuk Res. 2019 Nov;86:106222
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The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier
Mol Ther. 2019 May 8;27(5):912-921
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The metacaspase Yca1 maintains proteostasis through multiple interactions with the ubiquitin system
Cell Discov. 2019 Jan 22;5:6
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Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening
Adv Mater. 2019 Feb;31(7):e1806214
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Could Immunotherapy Sink Its Teeth into Lymphangioleiomyomatosis?
Am J Respir Cell Mol Biol. 2018 Dec;59(6):663-665
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Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy
Cancer Discov. 2018 Nov;8(11):1376-1389
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Metformin Preconditioning of Human-Induced Pluripotent Stem Cell-Derived Neural Stem Cells Promotes Their Engraftment and Improves Post-Stroke Regeneration and Recovery
Stem Cells Dev. 2018 Aug 15;27(16):1085-1096
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Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis
Cell Discov. 2018 May 1;4:21
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Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition
Theranostics. 2018 Feb 12;8(7):1766-1781
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Reprogramming patient-derived tumor cells generates model cell lines for tuberous sclerosis-associated lymphangioleiomyomatosis
Oncoscience. 2017 Nov 2;4(11-12):170-172
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Engineering PTEN-L for Cell-Mediated Delivery
Mol Ther Methods Clin Dev. 2017 Nov 21;9:12-22
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Human induced pluripotent stem cell-derived lung progenitor and alveolar epithelial cells attenuate hyperoxia-induced lung injury
Cytotherapy. 2018 Jan;20(1):108-125
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Micro-RNA Profiling of Exosomes from Marrow-Derived Mesenchymal Stromal Cells in Patients with Acute Myeloid Leukemia: Implications in Leukemogenesis
Stem Cell Rev Rep. 2017 Dec;13(6):817-825
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Concise Review: Musculoskeletal Stem Cells to Treat Age-Related Osteoporosis
Stem Cells Transl Med. 2017 Oct;6(10):1930-1939
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Human Pluripotent Stem Cell-Derived TSC2-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis
Cancer Res. 2017 Oct 15;77(20):5491-5502
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Direct reprogramming with SOX factors: masters of cell fate
Curr Opin Genet Dev. 2017 Oct;46:24-36
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Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape
Aging Cell . 2017 Aug;16(4):870-887
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Simple Silica Column-Based Method to Quantify Inorganic Polyphosphates in Cartilage and Other Tissues
Cartilage. 2018 Oct;9(4):417-427
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PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma
Cancer Res. 2016 Aug 15;76(16):4708-19.
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Human pluripotent stem cells
Methods. 2016 May 15;101:1-3
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